Transmission of Glomerulonephritis from Host to Human-Kidney Allotransplant

IN kidney transplantations between identical twins, when the recipient originally suffered from chronic glomerulonephritis, a major cause of late transplant failure has proved to be the development of glomerulonephritis in the transplanted kidney.1 , 2 In patients receiving a kidney allotransplant late failures are mostly due to a chronic allograft reaction in which vascular, not glomerular, lesions are an outstanding feature. Transmission of glomerulonephritis from host to transplant has not hitherto been described in a functioning renal allotransplant. This paper reports the clinical, serologic and pathological findings in a patient in whom glomerulonephritis developed in a kidney transplant received from her mother. . . .