David Casarett, Jason Karlawish, Pamela Sankar, Karen B. Hirschman, David A. Asch, Open Label Extension Studies & the Ethical Design of Clinical Trials, IRB: Ethics & Human Research, Vol. 23, No. 4 (Jul. - Aug., 2001), pp. 1-5
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Casarett et al. (2001) studied this question.
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