Key result
A novel reduced-order mathematical heart model based on active contraction rather than active stress provides a new mechanical interpretation of ventricular pressure-volume loops.
A novel reduced-order mathematical model of the left ventricle introduces the concept of active contraction to interpret pressure-volume loops, offering a new biomechanical perspective on cardiac pumping function.
We present a reduced-order heart model with the aim of introducing a novel point of view in the interpretation of the pressure-volume loops. The novelty of the approach is based on the definition of active contraction as opposed to that of active stress. The consequences of the assumption are discussed with reference to a specific pressure-volume loop characteristic of a normal human patient.
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Nardinocchi et al. (2010) studied Cardiac physiology. Reduced-order mathematical heart model was evaluated. A novel reduced-order mathematical heart model based on active contraction rather than active stress provides a new mechanical interpretation of ventricular pressure-volume loops.
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