Key result
Evaluating right ventricular function using 3D echocardiography and speckle tracking analysis may help detect cancer therapy-induced cardiotoxicity as early as or earlier than left ventricular assessment.
Why the study?
Anticancer therapy frequently damages the right ventricle as often or earlier than the left ventricle, prompting the development of right ventricular assessment techniques to detect cardiotoxicity.
Does right ventricular function assessment improve the early detection of cancer therapy cardiotoxicity in patients undergoing anticancer therapy?
Does right ventricular function assessment improve the early detection of cancer therapy cardiotoxicity in patients undergoing anticancer therapy?
Assessment of right ventricular function using advanced echocardiographic techniques may allow for earlier detection of chemotherapy-induced cardiotoxicity compared to traditional left ventricular monitoring.
May support earlier RV monitoring during cancer therapy; leaves open need for prospective validation vs standard LV assessment.
Advances in cancer treatment resulted in augmented patient survival rate. However, anticancer therapy often causes heart damage in the form of a progressive systolic heart failure. Echocardiographic parameters of left ventricular function were conventionally used to detect early manifestations of cancer therapy cardiotoxicity. Improved diagnosing of the right ventricle condition revealed that it is negatively affected by chemotherapy as frequently as the left ventricle, and sometimes even earlier than the latter. Hence, currently, the right ventricle function and mechanics assessment techniques are actively developed for the chemotherapy cardiotoxicity diagnostic, primarily employing 3D echocardiography and speckle tracking analysis. The presented review provides relevant information on the matter and highlights insufficiently developed issues and fields of further research.
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А. Н. Сумин (2021) conducted a review in Cancer therapy cardiotoxicity. Anticancer therapy was evaluated. Evaluating right ventricular function using 3D echocardiography and speckle tracking analysis may help detect cancer therapy-induced cardiotoxicity as early as or earlier than left ventricular assessment.
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