Key result
Carotid artery stenting resulted in a similar rate of primary adverse cardiovascular and cerebrovascular events compared to carotid endarterectomy (7.14% vs 11.43%, P>0.05) in patients with high-risk carotid stenosis.
Why the study?
Does carotid artery stenting compared to carotid endarterectomy improve clinical outcomes and safety in patients with high-risk carotid stenosis?
Cohort (n=63)
Yes
Does carotid artery stenting compared to carotid endarterectomy improve clinical outcomes and safety in patients with high-risk carotid stenosis?
Carotid artery stenting and carotid endarterectomy demonstrate similar short-term efficacy and safety profiles in patients with high-risk carotid stenosis.
May support stenting as alternative in high-risk stenosis; leaves open confirmation by randomized trials.
Objective: To analyze the clinical effects and safety of carotid endarterectomy (CEA) and carotid artery stenting (CAS) in the treatment of high-risk carotid stenosis patients.Methods: Total 63 patients who underwent CEA or CAS in our hospitals from January 2007 to December 2012 were selected in this study, and were randomly divided into an observation group and a control group. The patients in the observation group were subjected to CAS and those in the control group were subjected to CEA to compare the primary and secondary endpoints of the treatment.Results: The arrival rates of the primary and secondary endpoints were 7.14% and 10.71% respectively in the observation group, while those were 11.43% and 11.43% respectively in the control group. There were no significant differences in the arrival rates of primary and secondary endpoints between the two groups (P > 0.05).Conclusion: The efficacies and safety of CAS and CEA are similar in treating high-risk carotid stenosis patients.doi: http://dx.doi.org/10.12669/pjms.296.3971How to cite this:Wang P, Liang C, Du J, Li J. Effects of carotid endarterectomy and carotid artery stenting on high-risk carotid stenosis patients. Pak J Med Sci 2013;29(6):1315-1318.
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Wang et al. (2013) conducted a cohort in High-risk carotid stenosis (n=63). Carotid artery stenting (CAS) vs. Carotid endarterectomy (CEA) was evaluated on Adverse events of cardiovascular diseases, death and stroke within 1 month, and ipsilateral stroke or death during 6 months of follow-up (p=>0.05). Carotid artery stenting resulted in a similar rate of primary adverse cardiovascular and cerebrovascular events compared to carotid endarterectomy (7.14% vs 11.43%, P>0.05) in patients with high-risk carotid stenosis.
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