Response to Comment on Kahn and Davidson. The Reality of Type 2 Diabetes Prevention. Diabetes Care 2014;37:943–949

We appreciate the opportunity to respond to Gregg et al. (1) regarding our commentary on community-based lifestyle modification programs to prevent diabetes (2). Gregg et al. believe that we have a disagreement over the interpretation of the extant data and that in our analysis we ignored other important findings of the landmark trials. Gregg et al. (1) cite the 2012 systematic review by Ali et al. (3) (which we discussed in our article) as evidence that in community programs “an average 4% weight loss was observed” (1), which Gregg et al. believe is “comparable” to the major prevention trials. What Gregg et al. (1) ignore is the fact that the duration of the intervention and follow-up in 24 of the 28 studies in the Ali article was less than 1 year— most were 3–9 months; only 4 had a duration of 1 year. As we showed (2), which was also confirmed in a …