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The rate of synthesis of Bence Jones proteins in 5 multiple myeloma patients was calculated from turnover studies and immunoassay in serum. Calculations were made of correlations between turnover parameters and the renal function in the myeloma patients and in 7 patients with renal disease. The fractional catabolic rate and the proteinuric rate were significantly correlated with the serum creatinine.
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Kristian K. Jensen (1970) studied this question.
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