Key result
Infusion of [3H]testosterone, but not 51Cr-labelled red blood cells, into the ovarian vein resulted in radioactivity in ovarian arterial blood and tissue, indicating counter-current transfer.
Population
Cyclic sows (ovarian vascular pedicle model)
Comparison
Infusion of [3H]Testosterone for 30 min through… vs Infusion of 51Cr-labelled red blood cells in the…
Design
Preclinical
Follow-up
30 minutes
Authors
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Supports local androgen transfer in porcine ovary; leaves open human applicability and clinical relevance.
The study demonstrates the existence of a counter-current transfer mechanism for testosterone in the sow ovarian vascular pedicle.
Krzymowski et al. (1981) studied this question. [3H]Testosterone or 51Cr-labelled red blood cells infusion was evaluated on Radioactivity in ovarian arterial blood and ovarian tissue. Infusion of [3H]testosterone, but not 51Cr-labelled red blood cells, into the ovarian vein resulted in radioactivity in ovarian arterial blood and tissue, indicating counter-current transfer.
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