In search for novel antimicrobial and antineoplastic agents, the synthesis of some substituted arylidenepyruvic acid (phthalazin‐l‐yl)hydrazones 3 and their cyclodehydration to 3‐substituted 4H‐[1,2,4]triazino[3,4‐α] phthalazin‐4‐ones 4 is reported. Compounds 4a, 4b and 7 were screened for in vitro antibacterial and antifungal activities and were inactive.
No takes yet. Share an insight, caveat, or question.
Soliman et al. (1981) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: