Benzoylecgonine reacted with tetramethylethylenediamine to form a lipophilic ion pair, which was alkylated in the absence of water. The ethyl ester was readily recrystallized for pharmacological studies.
No takes yet. Share an insight, caveat, or question.
Brzezinski et al. (1992) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: