Effect of Pyridoxine Deficiency on Cholcsterol and Polyenoic Fatty Acids in Chicks

Summary. The influence of pyridoxine deficiency on chicks fed fat‐free and 10% peanut oil‐diets with and without 1 % cholesterol was studied. Cholesterol: The pyridoxine‐deficient diets caused significantly higher plasma cholesterol than the diets with added pyridoxine. The aorta vliolcsterol showed changes in the same direction. Liver chiolesterol was not, significantly affectd. The pyridoxine‐deficient diets caused lower cholesterol content in the heart than did the supplemented diets. Polyevie fatty acids: With a fat‐free, pyrudixine‐deficient diet a marked content of tetraenoic acid was found in heart and liver, whereas the tritenoic acid was proportionally decreased. Feeding of 10% peanut oil without pyridoxine caused less deposition of tetraenoic in heart and especially in the liver than feeding of 10 % peanut oil with pyridoxine. Addition of 1% cholesterol to the diets resulted in a decrease in the amount of tetraenoic acid in heart and liver.