Summary. 1. The precipitation limits for fibrinogen have been studied under various conditions. 2. The purification of fibrinogen solutions has been investigated and a method for the preparation of a purified prothrombin‐free fibrinogen solution from ox plasma is described. 3. The measurement of thrombin by employment of ammonium sulphate precipitated fibrinogen has been described. Mellanby fibrinogen is unsuitable for measuring of thrombin. 4. Fibrinogen shows rather high solubility in half‐saturated sodium chloride. This work was aided by grants from “Danmarks tekniske Højskoles Fond for teknisk Kemi” and from “Løvens kemiske Fabrik”, Copenhagen.
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Astrup et al. (1942) studied this question.
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