Population
Human plasma chylomicrons obtained from 1 subject with hypertriglyceridaemia, and human liver membranes
Comparison
Incubation of radioactively labelled plasma… vs Incubation with 20-fold excess of LDL
Design
Preclinical
Authors
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Binding data support chylomicron-specific hepatic sites distinct from LDL receptors; leaves open their in vivo role and clinical relevance.
This in vitro study demonstrates that human plasma chylomicrons bind to human liver membranes via specific sites distinct from LDL receptors, involving both Ca2+ dependent and independent mechanisms.
Claes‐Henrik Florén (1985) studied this question.
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