3D Printing of Aniline Tetramer‐Grafted‐Polyethylenimine and Pluronic F127 Composites for Electroactive Scaffolds

Electroactive hydrogel scaffolds are fabricated by the 3D‐printing technique using composites of 30% Pluronic F127 and aniline tetramer‐grafted‐polyethylenimine (AT‐PEI) copolymers with various contents from 2.5% to 10%. The synthesized AT‐PEI copolymers can self‐assemble into nanoparticles with the diameter of ≈50 nm and display excellent electroactivity due to AT conjugation. The copolymers are then homogeneously distributed into 30% Pluronic F127 solution by virtue of the thermosensitivity of F127, denoted as F/AT‐PEI composites. Macroscopic photographs of latticed scaffolds elucidate their excellent printability of F/AT‐PEI hydrogels for the 3D‐printing technique. The conductivities of the printed F/AT‐PEI scaffolds are all higher than 2.0 × 10−3 S cm−1, which are significantly improved compared with that of F127 scaffold with only 0.94 × 10−3 S cm−1. Thus, the F/AT‐PEI scaffolds can be considered as candidates for application in electrical stimulation of tissue regeneration such as repair of muscle and cardiac nerve tissue.