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April 25, 2006Organic LettersOpen Access

Formal Total Synthesis of the Cytotoxic Marine Ascidian Alkaloid Haouamine A

Jeannie H. Jeong Steven M. Weinreb

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Abstract

[reaction: see text] Described is a convergent 13-step synthesis of a pentacyclic compound which has previously been transformed into haouamine A, therefore constituting a formal total synthesis of this unique marine alkaloid.

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Cite This Study

Jeong et al. (2006) studied this question.

synapsesocial.com/papers/6a9df98c0da0fdae041058c6 https://doi.org/10.1021/ol060556c

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Haouamines A and B: A New Class of Alkaloids from the Ascidian Aplidium haouarianumOriginal Research · 2002 · 104 citations
2Facile Synthesis of the Indeno-Tetrahydropyridine Core of Haouamine AOriginal Research · 2005 · 42 citations
3Synthetic Studies toward the HaouaminesOriginal Research · 2005 · 36 citations
4Synthesis of the 3-Aza-[7]-paracyclophane Core of Haouamine A and BOriginal Research · 2006 · 37 citations
5Total Synthesis of (±)-Haouamine AOriginal Research · 2006 · 142 citations

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