To determine whether the high FSH levels present before day 20 in female rats are of importance for normal follicular development, the effect of depression of FSH levels on numbers of medium and large follicles was studied. Two approaches have been applied : depression of FSH and LH levels by injection of testosterone propionate (TP) and elimination of circulating FSH by a specific antiserum to FSH.
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Uilenbroek et al. (1976) studied this question.