An array of efficient catalytic transformations has been employed for the first stereoselective total synthesis of the lipid phthiocerol dimycocerosate A (PDIM A). It has been shown previously that this cell-wall-associated lipid, the structure of which has now been confirmed, is required for Mycobacterium tuberculosis virulence.
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Casas‐Arcé et al. (2008) studied this question.
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