⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

January 1, 1992Synthesis

Studies on Organophosphorus Compounds; LXIII. A New and Facile Synthetic Route to Protected Phosphonodipeptides: A Backbone for the Formation of Oligophosphonopeptides

Chengye Yuan Shoujun Chen

View at Publisher

Ask AI

Bookmark

Share

Abstract

All articles of this category A modified three-component condensation of 2-haloalkanamides, benzaldehydes and dialkyl phosphites leading to α-(2-haloacylamino)-substituted dialkyl benzylphosphonates 1 is described. Compounds 1 upon reaction with phthalimide and potassium carbonate under phase transfer catalysis conditions afford protected phosphonodipeptides, which can be used as important intermediates for the synthesis of oligophosphonopeptides.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Yuan et al. (1992) studied this question.

synapsesocial.com/papers/6a9e005f5924b374fbf9a3b4 https://doi.org/10.1055/s-1992-26319

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 related papers. Consider them for comparative context:

1Streamlined Synthesis of Di-ω-(pyren-1-yl)alkanoylphosphatidylcholine Lipids from 5-(Pyren-1-yl)-1-pentene: Fluorescent Probes for Sensing Amphiphilic Membrane Lateral PressureSynthesis · Tue,
2Electrophile-Promoted Stereospecific 1,2- and 1,3-Migrations of AlkynylboronatesSynthesis · Mon,
3Selective Synthesis of a Phosphine Sulfide-Capped Hexasulfide by the Reaction of a Stable Dialkylphosphinyl Radical with Elemental SulfurSynthesis · Mon,
4DNA-encoded Ugi reactions in the organic phase: Lactam synthesis and use of cyclic ketones as scaffold-providing oxo-componentSynthesis · Fri,
5Silver-Catalyzed C-C Fragmentation of Homobenzylic Alcohols: Convenient Synthesis of Fluoromethylated ArenesSynthesis · Fri,

More from Synthesis

t- BuONO-Mediated Direct C–H Functionalization for the Synthesis of Quinoxalin-2(1H)-ones in WaterFri,
Nickel-Catalyzed Asymmetric Propargylic Alkylation via Photocatalytic Nucleophile GenerationTue,
Visible-Light-Mediated Decarboxylative Coupling of Aromatic Carboxylic Acids with Aryl Methyl Ketones to Unsymmetrical 1,2-DiketonesFri,
Potassium Iodide as a Green Electrolyte and Redox Mediator in Electro-Organic Synthesis: Recent Advances and Mechanistic InsightsWed,
Novel Approach to Bridged Polynuclear Dihydroanthracene Systems via Regioselective Intramolecular Diels–Alder ReactionThu,