Key result
Extracorporeal irradiation of the blood prior to immunization did not attenuate or abolish the primary immune response to brucella antigen in uremic patients on chronic hemodialysis.
Why the study?
Does extracorporeal irradiation of the blood attenuate the primary immune response to brucella antigen in uremic patients on chronic hemodialysis?
Observational (n=7)
Does extracorporeal irradiation of the blood attenuate the primary immune response to brucella antigen in uremic patients on chronic hemodialysis?
Extracorporeal irradiation of the blood does not appear to attenuate the primary immune response to brucella antigen in uremic patients on chronic hemodialysis.
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Does not blunt brucella response in hemodialysis patients; hypothesis-generating, needs prospective confirmation before any clinical consideration.
Weeke et al. (1972) conducted an observational in Uremia (n=7). Extracorporeal irradiation of the blood (ECIB) vs. Vaccination without preceding ECIB was evaluated on Primary immune response to brucella antigen (cellular and humoral hypersensitivity). Extracorporeal irradiation of the blood prior to immunization did not attenuate or abolish the primary immune response to brucella antigen in uremic patients on chronic hemodialysis.
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