Key result
Over the past 40 years, vascular tissue engineering has advanced from early failures using isolated components to the development of more complete vascular grafts replicating arterial functions.
This review highlights the 40-year evolution of tissue-engineered vascular grafts from simple isolated components to complex structures replicating arterial function.
Over the past 40 years, remarkable advances have been made in our understanding of successful blood vessel regeneration, starting with the failures of early tissue-engineered vascular grafts designed using isolated components or molecules, such as collagen gels. The vascular tissue engineers are today better educated and have steered ongoing research developments toward clinical developments of more complete vascular grafts that replicate the multitude of specialized arterial aspects required for function.
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Dimitrievska et al. (2017) conducted a review in Blood vessel regeneration. Tissue-engineered vascular grafts was evaluated. Over the past 40 years, vascular tissue engineering has advanced from early failures using isolated components to the development of more complete vascular grafts replicating arterial functions.
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