Association Between Thrombogenicity Indices and Coronary Microvascular Dysfunction in Patients With Acute Myocardial Infarction

Figures

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  Figure 1. Measurements from Intracoronary Physiologic Testing and Thromboelastography (A) Index of microcirculatory resistance. (B) Thromboelastography. α = the angle in degrees formed by the tangent line to the thromboelastography tracing measure at the reaction time; CFR = coronary flow reserve; EPL = estimated percent lysis; IMR = index of microcirculatory index; K = coagulation time; LY30 = percentage of the clot that has lysed 30 minutes after the time of maximum amplitude; MA = maximum amplitude; R = reaction time; Tmn = mean transit time.

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  Figure 2. Flow Diagram of the Study AMI = acute myocardial infarction; IMR = index of microcirculatory resistance; MI = myocardial infarction; NYHA = New York Heart Association; PCI = percutaneous coronary intervention.

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  Figure 3. Thromboelastography Measurement in the CMD Versus Non-CMD Groups CMD = coronary microvascular dysfunction; P-FCS = platelet-fibrin clot strength; other abbreviations as in Figure 1.

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  Figure 4. Association Between P-FCS and CMD Occurrence (A) Distribution of P-FCS and prevalence of CMD. (B) Receiver-operating characteristic curve analysis: the optimal cutoff of P-FCS for CMD. (C) Risk of high P-FCS for CMD occurrence. OR = odds ratio; other abbreviations as in Figures 1 and 3.

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  Figure 5. Kaplan-Meier Curves of 3-Year MACE (A) Groups divided by IMR. (B) Groups divided by CFR. (C) Groups divided by IMR and P-FCS. (D) Groups divided by CFR and P-FCS. CFR = coronary flow reserve; MACE = major adverse cardiovascular events; other abbreviations as in Figures 1 and 3.