Over the past two years, there has been great interest in a newly recognized herpesvirus, called both Kaposi's sarcoma–associated herpesvirus (KSHV) and human herpesvirus 8. A piece of the viral genome was initially found in Kaposi's sarcoma tissue by an imaginative cloning method that identified abnormal DNA sequences.1 With only a fragmentary DNA sequence to go by, the polymerase chain reaction (PCR) was used to demonstrate this sequence in a majority of patients with AIDS-associated or classic types of Kaposi's sarcoma,1,2 as well as in two other cancers associated with AIDS — Castleman's disease and body-cavity–based lymphoma.35 In . . .
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Edward S. Mocarski (1997) studied this question.
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