The finding ofTreponema pallidum1in the substance of the brains of paretics has now been confirmed by several investigators in this country and abroad. Since the first report in which thepallidumwas described as having been discovered in twelve of the seventy brains from which sections had been studied, I have now found the spirochetes in thirty-six of one hundred and thirty additional brains, from which sections stained by the modified Levaditi method2were examined. Thus, in two hundred cases of paresis so far studied thepallidumhas been seen by me in forty-eight, or in nearly 25 per cent. of the specimens. I have, moreover, also succeeded in finding the micro-organism in one of twelve specimens of the spinal column, studied from cases of tabes dorsalis. A spiral organism morphologically identical with thepallidumwas in this instance found in the posterior columns of the
No takes yet. Share an insight, caveat, or question.
Hideyo Noguchi (1913) studied this question.