Mice persistently infected with lactic dehydrogenase virus (LDV) show granular deposits of host IgG, C3 and viral antigen in their renal glomeruli. Specific anti-LDV antibody is concentrated in these deposits. The mild glomerulonephritis observed is apparently related to trapping of circulating virus-antibody complexes in the glomerular filter.
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Oldstone et al. (1971) studied this question.