The synthesis of (±)-Indolizidine167B has been accomplished in 4 steps and 13.5 % overall yield from 4-carboxyethyl-4-(pyrrol-1-yl)butanal (1) via successive manipulations of 5,6-dihydroindolizine intermediates and final diastereoselective hydrogenation .
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Settambolo et al. (2005) studied this question.