Key result
Statin therapy for primary prevention of atrial fibrillation provides greater benefit in patients with higher CHADS2 and CHA2DS2VASc scores compared to those with lower scores.
Why the study?
Does statin therapy prevent atrial fibrillation in patients at risk, guided by CHADS2/CHA2DS2VASc scores?
Does statin therapy prevent atrial fibrillation in patients at risk, guided by CHADS2/CHA2DS2VASc scores?
CHADS2 and CHA2DS2VASc scores may be useful tools to identify patients who would derive the most benefit from statin therapy for the primary prevention of atrial fibrillation.
Answers are grounded in this paper and cite their sources.
May guide statin selection for AF prevention via higher CHADS2/CHA2DS2-VASc; leaves open randomized confirmation.
Atrial fibrillation (AF) is the most common arrhythmia and is associated with increased cardiovascular morbidity and mortality. The anti-arrhythmic effect of statins on AF prevention appears to be highly significant in most clinical studies. However, some discrepancies do exist among different clinical studies. Different clinical settings and types of stains used may explain these differences between trials. The CHADS2 and CHA2DS2VASc scoring systems have been used for stroke risk stratification in AF patients. The recent study suggested that these scores can also be used to guide statin therapy for AF prevention. Patients with higher scores had a higher risk of developing AF and gained more benefits from statins therapy than those with lower scores. This review article focused on the ability of these scores to predict AF prevention by statins.
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Hung et al. (2014) conducted a review in Atrial fibrillation. Statins was evaluated on Primary prevention of atrial fibrillation. Statin therapy for primary prevention of atrial fibrillation provides greater benefit in patients with higher CHADS2 and CHA2DS2VASc scores compared to those with lower scores.
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