This report surveys literature on four syndromes with major manifestations in the craniofacial region, i.e., Laband syndrome, de Barsy syndrome, Wiedemann-Rautenstrauch syndrome, and LADD syndrome. In general, these four syndromes are better described in the European than in the North American literature. In addition, we report on a newly diagnosed woman having the Laband syndrome and normal intelligence. Finally, we describe a possibly "new" craniofacial syndrome in a mother and her son.
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Beemer et al. (1988) studied this question.
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