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A porous-silicon microcavity membrane sensor maintains good sensitivity (see Figure) and shows long-term stability when embedded in a hydrogel matrix. The microcavity is sensitive to a 104–10–3 change in refractive index and can detect the binding of small molecules, proteins, etc., when they cause a sufficient change in the matrix porosity. This work represents a significant step towards realizing a “smart bandage” concept for wound-care management.
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DeLouise et al. (2005) studied this question.
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