Key result
Standardized in vitro and in vivo test protocols for the performance validation of a totally implantable artificial heart were established and proposed as simple, easy, and inexpensive methods.
Population
In vitro and in vivo models for total artificial heart (TAH) testing
Design
Preclinical
Authors
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Proposed protocols may simplify preclinical TAH validation; leaves open clinical translation from animal data.
The paper proposes standardized, simple, and inexpensive in vitro and in vivo testing protocols for the validation of total artificial hearts.
Orime et al. (1994) studied Total artificial heart validation. Standardized in vitro and in vivo validation tests was evaluated. Standardized in vitro and in vivo test protocols for the performance validation of a totally implantable artificial heart were established and proposed as simple, easy, and inexpensive methods.
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