Concerning the Localization of End Groups in Dendrimers

The different generations of BOC-protected glycine-functionalized PAMAM dendrimers were studied, crystal structure of the 1st generation dendrimer was obtained, and the amt. of H bonds was estd. The x-ray structure shows multiple interactions between the different end groups of the dendrimer, modeling the shell of a higher generation dendrimer. Spectroscopic results from solns. of all dendrimers of all generations confirm the close proximity of end groups