A strain of fixed rabies virus adapted to hamster kidney tissue cells has produced culture fluids of high infectivity for rabbits and mice. These culture fluids were rendered non-infective by treatment with formaldehyde at a concentration of 8 m M. Rabbits immunized with this material produced autirabies antibody to a high titer and were subsequently proved to be resistant to intramuscular inoculation of rabies virus from the salivary glands of a naturally infected fox.
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P Fenje (1960) studied this question.
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