histamines, which were significantly associated with motorcycle accidents (although not with road accidents of all types).Dr Wheatley repeats his previous assertion' that general practitioners usually warn patients about possible effects of tranquillisers on driving skills, but he does not cite any evi- dence to support it.Unfortunately, the type of warning that he describes could not be relied on to prevent accidents, because it is postulated that tranquillisers "produce subtle effects undetected by the patient."In tests of low- speed vehicle handling, Betts and his col-leagues2 showed that drivers whose performance was affected by tranquillisers did not experience subjective effects.
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J Jefferiss (1979) studied this question.