In Situ Replication Techniques: I. Preliminary Screening and the Negative Replication Technique

Fourteen commercially available elastomeric materials were investigated for their suitability as in vivo replication media. After a preliminary screening on an annotated specimen, three materials were chosen for further study. Of all materials evaluated, Xantopren Blue and Silene silicone impression materials provided the best results in vivo. This study demonstrates that a high resolution (ca 1 micron) negative replication technique may prove useful for the clinical evaluation of single-surface phenomena.