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Case Studies1 June 1966Human Rabies After Antiserum and Vaccine Postexposure TreatmentCase Report and ReviewJOHN A. ANDERSON, M.D., FRANK T. DALY JR., M.D., JACK C. KIDD, M.D.JOHN A. ANDERSON, M.D., FRANK T. DALY JR., M.D., JACK C. KIDD, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-6-1297 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPhysicians all over the world are making decisions daily on the treatment of animal bites to protect their patients from rabies. This case report is presented to demonstrate that supposedly adequate postexposure antirabies care may fail to protect the individual against rabies. A review of such failures is also presented.CASE REPORTOn May 8, 1964, the 8-year-old dependent son of a member of the U. S. Air Force, stationed in Rabat, Morocco, was bitten by his own dog on the face. The attack was unprovoked. The dog was an adult German shepherd that had no immunization history, having been...References1. KOPROWSKIVAN DER SCHEERBLACK HJJ: Use of hyperimmune antirabies serum concentrates in experimental rabies. Amer. J. Med. 8: 412, 1950. CrossrefMedlineGoogle Scholar2. HABEL K: Antiserum in prophylaxis of rabies. Bull. WHO 10: 781, 1954. MedlineGoogle Scholar3. BALTAZARDGHODSSI MM: Prevention of human rabies. Treatment of persons bitten by rabid wolves in Iran. Ibid., p. 797. Google Scholar4. BALTAZARDBAHMANYAR MM: Essai pratique du serum antirabique chez les mordus par loups enragés. Bull. WHO 13: 747, 1955. MedlineGoogle Scholar5. SABETIBAHMANYERGHODSSIBALTAZARD AMMM: Traitement des mordus par loups enragés en Iran. Situation actuelle. Ann. Inst. Pasteur (Paris) 106: 303, 1964. MedlineGoogle Scholar6. SABETIFATHIBAHMANYERBALTAZARD AMMM: Eches éloignés du traitement antirabique. Ibid., p. 307. Google Scholar7. NOURY M: Sur l'importance de la rage au Maroc. Maroc Med. 42: 461, 1963. MedlineGoogle Scholar8. BOVINE M: Antirabies serum used in treatment of bites on the face in North Vietnam. Ann. Inst. Pasteur (Paris) 94: 384, 1958. MedlineGoogle Scholar9. TIERKEL E: Human rabies deaths 1946-1964. Communicable Disease Center, Rabies Control Unit Report, Atlanta, Ga. Unpublished data. Google Scholar10. HILDRETH EA: Prevention of rabies, or the decline of Sirius. Ann. Intern. Med. 58: 883, 1963. LinkGoogle Scholar11. HABELKOPROWSKI KH: Laboratory data supporting the clinical trial of antirabies serum in persons bitten by a rabid wolf. Bull. WHO 13: 773, 1955. MedlineGoogle Scholar12. DEANSHERMAN DJI: Potency of commercial rabies vaccine used in man. Public Health Rep. 77: 705, 1962. CrossrefMedlineGoogle Scholar13. HUMPHREYKEMPWOOD GLGEEG: A fatal case of rabies in a woman bitten by an insectiverous bat. Public Health Rep. 75: 317, 1960. CrossrefMedlineGoogle Scholar14. ATANASIUBAHMANYARBALTAZARDFOXHABELKAPLANKISSLINGKOMAROVKOPROWSKILÉPINEPEREZ GALLARDOSCHAEFFER PMMJPKMMREAHPFM: Rabies neutralizing antibody response to different schedules of serum and vaccine inoculates in non-exposed person. Bull. WHO 14: 593, 1956. MedlineGoogle Scholar15. HABEL K: Rabies prophylaxis in Iran. Public Health Rep. 72: 667, 1957. CrossrefMedlineGoogle Scholar16. Expert Committee on Rabies, fourth report. WHO Techn. Rep. Ser. 201, 1960. Google Scholar17. HABEL K: Personal communication. Google Scholar18. GREENBERGCHILDRESS MJ: Vaccination against rabies with duck-embryo and Semple vaccines. JAMA 173: 333, 1960. CrossrefMedlineGoogle Scholar19. HILDRETH EA: Personal communication. Google Scholar20. DEANBAERTHOMPSON DJGMWR: Studies on the local treatment of rabies-infected wounds. Bull. WHO 28: 477, 1963. MedlineGoogle Scholar21. CONSTANTINESCUZAVATEMORARU NOA: Capacitatea protectoare a serului antirabic administrat pe diferite car, in raport cu data infectici rabice. Stud. Cercet. Inframicrobiol. 13: 367, 1962. MedlineGoogle Scholar22. DEANEVANSMCCLURE DJWMRC: Pathogenesis of rabies. Bull. WHO 29: 803, 1963. MedlineGoogle Scholar23. HABEL K: Rabies antiserum interference with antigenecity of vaccine in mice. Bull. WHO 17: 933, 1957. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Newport, Rhode IslandFrom the U. S. Naval Hospital, Newport, R. I.Requests for reprints should be addressed to Lcdr. John A. Anderson, MC, USN, Department of Pediatrics, U. S. Naval Hospital, Newport, R. I. 02843. 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HATTWICK, M.D., GEORGE M. BAER, D.V.M., JEAN S. SMITH, B.S.Post-Exposure Prophylaxis of Murine Rabies with Polyinosinic-Polycytidylic Acid and Chlorite-Oxidized AmyloseThe vaccination of man and other animals against rabiesRecovery from Rabies A Case ReportMICHAEL A. W. HATTWICK, M.D., THOMAS T. WEIS, M.D., C. JOHN STECHSCHULTE, M.D., GEORGE M. BAER, D.V.M., MICHAEL B. GREGG, M.D.Human Rabies Encephalitis in VietnamLOUIS P. DEHNER, M.D.Infectious diseases. Annual review of significant publications. 1 June 1966Volume 64, Issue 6Page: 1297-1302KeywordsAntigensDecision makingRabiesVaccines Issue Published: 1 June 1966 PDF DownloadLoading ...
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