Key result
Surgical treatment of a 78-year-old man with laryngeal malignant fibrous histiocytoma was followed by death at 8 months, highlighting the tumor's aggressive biological behavior.
Case Report (n=1)
Laryngeal malignant fibrous histiocytoma is a rare tumor with aggressive biological behavior that requires electron microscopy and immunohistochemical techniques for differential diagnosis.
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Suggests high post-resection mortality in laryngeal MFH; leaves open optimal management for this rare tumor.
Malignant fibrous histiocytoma (MFH) of the upper respiratory tract is rare. We report a case of laryngeal MFH in a 78-year-old man. The patient died 8 months after the first surgical treatment. The clinicopathologic features are described, and the importance of electron microscopy and immunohistochemical techniques in the differential diagnosis with so-called "sarcomatoid carcinoma" is stressed. The tumor has an aggressive biological behavior and tends to recur and metastasize.
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Rosa et al. (1990) conducted a case report in Laryngeal Malignant Fibrous Histiocytoma (n=1). Surgical treatment was evaluated on Survival. Surgical treatment of a 78-year-old man with laryngeal malignant fibrous histiocytoma was followed by death at 8 months, highlighting the tumor's aggressive biological behavior.
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