Key result
Transplantation of the right donor kidney to the left side of the recipient rat resulted in no morphological differences compared to conventionally transplanted kidneys.
A new technique for transplanting both kidneys from a single donor rat is feasible and yields similar graft morphology to conventional methods, reducing the number of donor animals required.
We have developed a technique for harvesting and transplanting two kidneys from one donor rat. Our method involves end-to-end anastomosis of the renal artery and the renal vein. Because of the short distance between the caudal vena cava and the right kidney, renal transplantation is not feasible on the right side of the recipient. The right donor kidney was therefore transplanted to the left side. Graft morphology was assessed on paraffin sections. We observed no differences between conventionally transplanted kidneys (n = 116) and right kidneys transplanted according to the method described (n = 40). In conclusion, our technique is simple, saves time and reduces the number of donor rats.
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Grau et al. (2003) studied Kidney transplantation (animal model) (n=156). Transplantation of the right donor kidney to the left side vs. Conventionally transplanted kidneys was evaluated on Graft morphology assessed on paraffin sections. Transplantation of the right donor kidney to the left side of the recipient rat resulted in no morphological differences compared to conventionally transplanted kidneys.
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