Key result
Anxiety (OR 3.20; 95% CI 3.05-3.48) and depression (OR 3.26; 95% CI 3.12-3.49) independently increased the risk of atrial fibrillation recurrence after circumferential pulmonary vein ablation.
Why the study?
Does circumferential pulmonary vein ablation improve anxiety and depression, and do these psychological factors affect AF recurrence in patients with paroxysmal AF?
Population
210 patients with a diagnosis of paroxysmal atrial fibrillation
Comparison
Circumferential pulmonary vein ablation (CPVA) vs Antiarrhythmic drugs (medicine group)
Design
Cohort
Follow-up
1 year
Authors
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May warrant pre-ablation psychological screening; leaves open whether treating anxiety or depression reduces recurrence in prospective trials.
Cohort (n=210)
Does circumferential pulmonary vein ablation improve anxiety and depression, and do these psychological factors affect AF recurrence in patients with paroxysmal AF?
Odds Ratio: 3.2 (95% CI 3.05–3.48)
p-value: p=0.023
Circumferential pulmonary vein ablation improves anxiety, depression, and quality of life in paroxysmal AF patients, while higher baseline anxiety and depression independently predict a higher risk of AF recurrence.
Yu et al. (2012) conducted a cohort in Paroxysmal atrial fibrillation (n=210). Anxiety and depression (SAS and SDS scores) was evaluated on Atrial fibrillation recurrence after CPVA (OR 3.20, 95% CI 3.05-3.48, p=0.023). Anxiety (OR 3.20; 95% CI 3.05-3.48) and depression (OR 3.26; 95% CI 3.12-3.49) independently increased the risk of atrial fibrillation recurrence after circumferential pulmonary vein ablation.
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