A single oral dose (15 mg/kg body wt.) of Ochratoxin A caused a depletion of hepatic glycogen level and an elevation in the cardiac glycogen level in both intact and adrenalectomized rats. When tested in adrenalectomized rats under pre-treatment of hydrocortisone, Ochratoxin A showed similar effects on hepatic glycogen level as was seen in intact rats. These changes in hepatic glycogen levels of Ochratoxin A treated rats may be attributed to interference with endocrine balance.
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Suzuki et al. (1973) studied this question.
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