Key result
A one-year moderate physical training program reduced cardiovascular events by 50% and significantly improved exercise capacity, blood pressure, and cardiac function compared to standard therapy alone in post-myocardial infarction patients with arterial hypertension.
Why the study?
The clinical effectiveness of physical training in a Cardiac Rehabilitation Program needed assessment in hypertensive post-myocardial infarction patients.
Does a moderate physical training program improve exercise capacity, cardiac function, blood pressure, and clinical outcomes in hypertensive post-myocardial infarction patients?
RCT (n=206)
Prospectively randomized
Yes
Does a moderate physical training program improve exercise capacity, cardiac function, blood pressure, and clinical outcomes in hypertensive post-myocardial infarction patients?
Answers are grounded in this paper and cite their sources.
A moderate physical training program significantly improves exercise capacity, cardiac function, blood pressure, and reduces cardiovascular events in hypertensive post-MI patients.
The clinical effectiveness of physical training in a Cardiac Rehabilitation Program (CRP) was assessed in hypertensive (Arterial Hypertension, AH), post-Myocardial Infarction (MI) patients. 206 patients were randomized into a physically trained group (PhTG, n=102) and an untrained, control group (CG, n=104). All patients received standard drug therapy. PhTG patients performed mild callisthenic exercises and moderately intensive bicycle exercise three times/week for one year. Compared to control patients, PhTG patients had significant changes in exercise capacity (duration +38%, p<0.001; total work +63.6%, p<0.001); rate-pressure product (-8.2%, p<0.01); left ventricular ejection fraction (+7.6%, p<0.001); left ventricular stroke volume (+5.1%, p<0.01). Resting BP decreased in PhTG patients (systolic BP, -3.1%, p<0.05; diastolic BP, -3.5%, p<0.001), but increased in CG patients (systolic BP, +3.1%, p<0.05; diastolic BP +3.4%, p<0.05). PhTG patients had fewer myocardial ischemic episodes, including painless ischemia during exercise, fewer angina attacks, less nitroglycerin consumption, improved quality of life, fewer cardiovascular events (-50%, p<0.05), and days of absence from work (-43.2%, p<0.05). Thus, supplementing a CRP with moderate exercise improved BP, work capacity, cardiac function, and quality of life in hypertensive, post-MI patients.
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Dm et al. (2025) conducted an RCT in Arterial Hypertension and recent Acute Myocardial Infarction (n=206). Moderate physical training program vs. Standard medical therapy alone was evaluated on Cardiovascular events requiring medical evaluation (-50%, p=<0.05). A one-year moderate physical training program reduced cardiovascular events by 50% and significantly improved exercise capacity, blood pressure, and cardiac function compared to standard therapy alone in post-myocardial infarction patients with arterial hypertension.
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