Key result
Structural changes in peripheral pulmonary arteries, including the appearance of muscle in intra-acinar arteries, contribute to the rise in pulmonary artery pressure and vascular resistance.
Design
Review
Authors
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Should not yet change PH practice; extends pathologic descriptions but leaves open therapeutic implications.
Structural changes in peripheral pulmonary arteries, such as muscularization of intra-acinar arteries, directly contribute to increased pulmonary vascular resistance in chronic pulmonary hypertension.
Barbara Meyrick (1991) conducted a review in Acute lung injury and chronic pulmonary hypertension. Structural changes in peripheral pulmonary arteries, including the appearance of muscle in intra-acinar arteries, contribute to the rise in pulmonary artery pressure and vascular resistance.
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