Development of a dual-cure mineral trioxide aggregate-based cement: Biological, physical, and mechanical properties.

Laura Siqueira Pintado; Eliana do Nascimento Torre; Maicon Selayaran; Rodrigo Varella de Carvalho; César Henrique Zanchi; Fábio Renato Manzolli Leite; Adriana Etges

doi:10.4103/jcd.jcd_393_16

January 1, 2018Open Access

Development of a dual-cure mineral trioxide aggregate-based cement: Biological, physical, and mechanical properties.

View Full Paper

Ask AI

Bookmark

Share

Key Points

To compare the biological biocompatibility, physical behavior, and mechanical strength of a newly formulated dual-cure white mineral trioxide aggregate against conventional white mineral trioxide aggregate.
Assessed cytotoxicity and micronucleus formation across two distinct cell models, including human pulp fibroblasts (HPF).
Measured mechanical and physical material parameters, specifically diametral tensile strength, water solubility, and water sorption at a significance threshold of P < 0.05.
Neither cement demonstrated cytotoxic activity, but the dual-cure formulation uniquely promoted human pulp fibroblast growth.
Micronucleus frequencies for both cements remained statistically indistinguishable from control levels.
The dual-cure cement exhibited lower diametral tensile strength and reduced water solubility compared to conventional cement, while water sorption values were equivalent.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

In vitro study reveals dual-cure mineral trioxide aggregate stimulates cell growth without cytotoxicity, indicating potential utility as an effective dental restorative cement.

Abstract

PURPOSE: The purpose of this study is to compare the physical, mechanical, and biocompatibility properties of a new dual-cure white mineral trioxide aggregate (D-W-MTA) and a commercial W-MTA. MATERIALS AND METHODS: < 0.05. RESULTS: D-MTA and W-MTA not showed cytotoxic effect on the two cell lines. However, D-MTA stimulated HPF growth. The MN count was similar to that of the control group for D-MTA and W-MTA. D-MTA presented lower DTS and WSl. Nevertheless, WSp was similar in the two groups. CONCLUSION: tests should be performed to evaluate the performance of this material.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Pintado et al. (2018) studied this question.

synapsesocial.com/papers/6a9e6138251378b1b9acb8ee https://doi.org/10.4103/jcd.jcd_393_16

View Full Paper

Ask AI

Bookmark

Share

Development of a dual-cure mineral trioxide aggregate-based cement: Biological, physical, and mechanical properties.

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Development of a dual-cure mineral trioxide aggregate-based cement: Biological, physical, and mechanical properties.

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading