Hypersensitivity to fluoroquinolone: A case series

Fluoroquinolones are extensively used for empirical therapy of a wide range of infections because of their broad-spectrum bactericidal activity, oral efficacy, and good tolerability. Fixed drug eruption (FDE) is a form of drug-induced skin reaction marked by red rashes with sharp borders and erythematous lesions. FDEs are known to arise from a variety of medications such as analgesics, anticonvulsants, sedatives, and antibiotics. Among antibiotics, tetracyclines and fluoroquinolones are most commonly associated with FDE. The aim is to focus on the cutaneous adverse drug reaction caused by fluoroquinolones through a compilation of three case reports from the Dermatology Outpatient Department of Medical College, Baroda, and SSG Hospital.