Batch cooling crystallization of xylitol produced by biotechnological route

BACKGROUND: This work deals with the xylitol production by biotechnological routes emphasizing the purification process using crystallization. RESULTS: Xylitol volumetric productivity of 0.665 g L−1 h−1 and yield of 0.7024 g g−1 were obtained after 92 h fermentation. The fermented broth (61.3 g L−1 xylitol) was centrifuged, treated and concentrated obtain a syrup (745.3 g L−1 xylitol) which was crystallized twice, xylitol crystals with 98.5–99.2% purity being obtained. CONCLUSION: The hypothetical distribution obtained permits the determination of modeling parameters, which make possible the estimation of crystal dominant size from different initial experimental conditions.