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AB 2 C type four component quadruple cascade reaction between MBH acetate, 1,3-indanedione and aldehydes via [1 + 1 + 1 + 3] annulation progressed through Knoevenagel/Michael/Michael/Michael sequence for the synthesis of b is-spirocyclohexane.
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Gudise et al. (2023) studied this question.
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