How to fuse heterocycles: The direct enamine–imine isomerization of indoles and subsequent intramolecular imino-ene has been observed under Lewis acid catalysis. This unique reaction occurred for indoles that contain a tethered olefin functionality, and led to fused indoline heterocycles with excellent diastereocontrol (see scheme).
No takes yet. Share an insight, caveat, or question.
Han et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: