The author has given us a comprehensive treatise on anaphylaxis and sensitization, with special reference to diseases of the skin. He has made no attempt to describe the skin eruptions, but his purpose is to show the rôle played by anaphylaxis in the pathogenesis of various skin diseases. He starts out by presenting the different theories of anaphylaxis, describing in detail the work done and the experiments carried out by the workers on this subject. He then goes on to explain the rôle played by anaphylaxis in the production of skin diseases, especially those of unknown etiology. The reviewer takes exception to the author's inclusion of all tuberculids as sensitization phenomena due to the tubercle bacillus alone. The work of Guy, and more recently that of Chambers, have thrown some doubt on this explanation. The best part of the work is devoted to a description of the various tests for
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H. E. MacDermot (1925) studied this question.