The chemical transformation of the acetoxy ketone (5), which has previously been obtained from α-santonin, to (+)-junenol (1) and acolamone (3) has been carried out. In addition, isojunenol (2) was also derived from 5 via the trisubstituted olefin (9) which was obtained as the main product from the α- and β-oriented mesylates (8 and 11) on treatment with NaI in HMPA.
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Niwa et al. (1976) studied this question.