Mineral Oil Pneumonia

Case Studies1 October 1962Mineral Oil PneumoniaALBERT MILLER, M.D., RICHARD A. BADER, M.D., MORTIMER E. BADER, M.D., ALVIN S. TEIRSTEIN, M.D., IRVING J. SELIKOFF, M.D.ALBERT MILLER, M.D.Search for more papers by this author, RICHARD A. BADER, M.D.Search for more papers by this author, MORTIMER E. BADER, M.D.Search for more papers by this author, ALVIN S. TEIRSTEIN, M.D.Search for more papers by this author, IRVING J. SELIKOFF, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-4-627 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMineral oil pneumonia may be defined as the inflammatory, granulomatous, and fibrotic reaction of the lung to the aspiration of mineral oil. It is to be differentiated from endogenous lipoid pneumonias such as cholesterol pneumonia (resulting from the breakdown of bound intracellular lipids secondary to suppuration), fat embolism, and lipoid histiocytoses affecting the lung (1-3).The importance of aspirated oils in the production of pulmonary lesions was first recognized in animals, in 1920 (4, 5). In 1925, Laughlen (6) described 4 cases in man, due to mineral oil. Numerous case reports, postmortem findings, and reviews have appeared since (7-13).Mineral...References1. CLAGETTMCDONALD OTJR: Bronchiectasis and lipoid pneumonitis associated with a large aberrant pulmonary artery. Proc. Mayo Clin. 20: 1, 1945. Google Scholar2. MCDONALDHODGSON JRCH: The problem of lipoid pneumonia or granuloma of the lung. Med. Clin. N. Amer. July: 989, 1954. CrossrefMedlineGoogle Scholar3. BUECHNERSTRUG HALH: Lipoid granuloma of the lung of exogenous origin. Dis. Chest 29: 401, 1956. Google Scholar4. 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SHASHKASBAUFIELDROSENBAUM MWASI: Distribution effect and fate of oil aerosol particles retained in the lungs of mice. Arch. Industr. Hyg. Occup. Med. 1: 20, 1950. MedlineGoogle Scholar25. QUINNMEYER LHOO: Relationship of sinusitis and bronchiectasis. Arch. Otolaryng. (Chic.) 10: 152, 1929. CrossrefGoogle Scholar26. GUIDRYCLAGETTMCDONALDKINCAID LDOTJROW: Pulmonary resection for mineral oil granulomas. Ann. Surg. 150: 67, 1959. CrossrefMedlineGoogle Scholar27. FREIMANENGELBERGMERRITT DGHWH: Oil aspiration (lipoid) pneumonia in adults. Arch. Intern. Med. 66: 11, 1940. CrossrefGoogle Scholar28. IKEDA K: Lipoid pneumonia of adult type (paraffinoma) of the lung: report of five cases. Arch. Path. 23: 470, 1937. Google Scholar29. WOOD EH: Unusual case of carcinoma of both lungs associated with lipoid pneumonia. Radiology 40: 193, 1943. CrossrefGoogle Scholar30. BROWNBISKIND ALGR: Differential diagnosis between lipoid pneumonia and pulmonary neoplasm. Treatment by partial lobectomy. JAMA 117: 4, 1941. CrossrefGoogle Scholar31. RABINOVITCHLEDERER JM: Lipoid pneumonia. Arch. Path. 19: 160, 1934. Google Scholar32. BALDWINCOURNANDRICHARDS EDADW: Pulmonary insufficiency. III. A study of 122 cases of chronic pulmonary emphysema. Medicine 28: 201, 1949. CrossrefMedlineGoogle Scholar33. AUSTRIANMCCLEMENTRENZETTIRILEYDONALDCOURNAND RJHADRLKWA: The clinical and physiological features of some types of pulmonary diseases with impairment of alveolar-capillary diffusion. Amer. J. Med. 11: 667, 1951. CrossrefMedlineGoogle Scholar34. WRIGHTFILLEY GWGF: Pulmonary fibrosis and respiratory function. Amer. J. Med. 10: 642, 1951. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, New YorkFrom the Cardiopulmonary Laboratory, Department of Medicine, The Mount Sinai Hospital, New York, New York.This study was supported by the Robert S. Clark Foundation.Requests for reprints should be addressed to Mortimer E. Bader, M.D., The Mount Sinai Hospital, Fifth Avenue and One Hundredth Street, New York 29, New York. 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KUTTY, M.D.Drug Problems in the Geriatric PatientDrug-Induced Lung DiseasePulmonary aspirationA case of chronic paraffin pneumonitisROENTGENOGRAM OF THE MONTHDiffuse lipoid pneumonitis successfully treated with prednisoneLIPOID PNEUMONIA IN A GERIATRIC PATIENTEarly lipoid pneumonia 1 October 1962Volume 57, Issue 4Page: 627-634KeywordsFatsHospital medicineIngestionLesionsLipidsLungsOilsPartial pressure of carbon dioxidePneumoniaResearch laboratories Issue Published: 1 October 1962 PDF DownloadLoading ...