Editorials17 January 2012To Image or to Autopsy?Elizabeth C. Burton, MD and Mahmud Mossa-Basha, MDElizabeth C. Burton, MDFrom Johns Hopkins University, Baltimore, MD 21287. and Mahmud Mossa-Basha, MDFrom Johns Hopkins University, Baltimore, MD 21287.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-156-2-201201170-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail In the United States, autopsy rates have fallen precipitously since the 1970s to 4.3% for natural deaths occurring both inside and outside of the hospital (1). This decrease is mirrored worldwide. Reasons for the decline have long been debated and include diagnostic overconfidence, physician reluctance to pursue consent for autopsy, family reluctance to grant permission for autopsy, lack of regulatory rate requirements, and budgetary constraints. Despite this underutilization, autopsy remains the gold standard for determining the cause of death. It offers benefit for education, research, and quality improvement, particularly as applied to diagnostic accuracy and the potential to improve patient ...References1. Hoyert DL. The changing profile of autopsied deaths in the United States, 1972-2007. NCHS Data Brief, no 67. Hyattsville, MD: National Center for Health Statistics; 2011. Google Scholar2. Shojania KG, Burton EC, McDonald KM, Goldman L. Changes in rates of autopsy-detected diagnostic errors over time: a systematic review. JAMA. 2003;289:2849-56. [PMID: 12783916] CrossrefMedlineGoogle Scholar3. Dirnhofer R, Jackowski C, Vock P, Potter K, Thali MJ. VIRTOPSY: minimally invasive, imaging-guided virtual autopsy. Radiographics. 2006;26:1305-33. [PMID: 16973767] CrossrefMedlineGoogle Scholar4. Thali MJ, Yen K, Schweitzer W, Vock P, Boesch C, Ozdoba C, et al. Virtopsy, a new imaging horizon in forensic pathology: virtual autopsy by postmortem multislice computed tomography (MSCT) and magnetic resonance imaging (MRI)—a feasibility study. J Forensic Sci. 2003;48:386-403. [PMID: 12665000] CrossrefMedlineGoogle Scholar5. Donchin Y, Rivkind AI, Bar-Ziv J, Hiss J, Almog J, Drescher M. Utility of postmortem computed tomography in trauma victims. J Trauma. 1994;37:552-5. [PMID: 7932884] CrossrefMedlineGoogle Scholar6. Aghayev E, Christe A, Sonnenschein M, Yen K, Jackowski C, Thali MJ, et al. Postmortem imaging of blunt chest trauma using CT and MRI: comparison with autopsy. J Thorac Imaging. 2008;23:20-7. [PMID: 18347515] CrossrefMedlineGoogle Scholar7. Patriquin L, Kassarjian A, Barish M, Casserley L, O'Brien M, Andry C, et al. Postmortem whole-body magnetic resonance imaging as an adjunct to autopsy: preliminary clinical experience. J Magn Reson Imaging. 2001;13:277-87. [PMID: 11169835] CrossrefMedlineGoogle Scholar8. Weustink AC, Hunink MG, van Dijke CF, Renken NS, Krestin GP, Oosterhuis JW. Minimally invasive autopsy: an alternative to conventional autopsy? Radiology. 2009;250:897-904. [PMID: 19244053] CrossrefMedlineGoogle Scholar9. Shojania KG, Burton EC, McDonald KM, Goldman L. Overestimation of clinical diagnostic performance caused by low necropsy rates. Qual Saf Health Care. 2005;14:408-13. [PMID: 16326784] CrossrefMedlineGoogle Scholar10. Scholing M, Saltzherr TP, Fung Kon Jin PH, Ponsen KJ, Reitsma JB, Lameris JS, et al. The value of postmortem computed tomography as an alternative for autopsy in trauma victims: a systematic review. Eur Radiol. 2009;19:2333-41. [PMID: 19458952] CrossrefMedlineGoogle Scholar11. Thayyil S, Chandrasekaran M, Chitty LS, Wade A, Skordis-Worrall J, Bennett-Britton I, et al. Diagnostic accuracy of post-mortem magnetic resonance imaging in fetuses, children, and adults: A systematic review. Eur J Radiol. 2010;75:142-8. CrossrefGoogle Scholar12. Wichmann D, Obbelode F, Vogel H, Hoepker WW, Nierhaus A, Braune S, et al. Virtual autopsy as an alternative to traditional medical autopsy in the intensive care unit. A prospective cohort study. Ann Intern Med. 2012;156:123-30. LinkGoogle Scholar13. Kochanek KD, Xu JQ, Murphy SL, Minino AM, Kung HC. Deaths: preliminary data for 2009. National Vital Statistics Reports; vol 59, no 4. Hyattsville, MD: National Center for Health Statistics; 2011. Google Scholar14. Shojania KG, Burton EC, McDonald K, Goldman L. The Autopsy as an Outcome and Performance Measure. Evidence Report/Technology Assessment no. 58 (Prepared by the University of California at San Francisco-Stanford Evidence-based Practice Center under contract no. 290-97-0013). AHRQ Publication no. 03-E002. Rockville, MD: Agency for Healthcare Research and Quality; 2002. Google Scholar15. Brennan TA, Leape LL, Laird NM, Hebert L, Localio AR, Lawthers AG, et al. Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study I. N Engl J Med. 1991;324:370-6. [PMID: 1987460] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Elizabeth C. Burton, MD; Mahmud Mossa-Basha, MDAffiliations: From Johns Hopkins University, Baltimore, MD 21287.Acknowledgment: The authors thank Katie Flickinger, MS, for providing insightful comments and helpful feedback on the draft of this article.Disclosures: None disclosed. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M11-2725.Corresponding Author: Elizabeth C. Burton, MD, Johns Hopkins University School of Medicine, Pathology Building, Room B106, 600 North Wolfe Street, Baltimore, MD 21287; e-mail, eburton3@jhmi.edu.Current Author Addresses: Dr. Burton: Johns Hopkins University School of Medicine, Pathology Building, Room B106, 600 North Wolfe Street, Baltimore, MD 21287.Dr. Mossa-Basha: Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, 600 North Wolfe Street, Baltimore, MD 21287. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoVirtual Autopsy as an Alternative to Traditional Medical Autopsy in the Intensive Care Unit Dominic Wichmann , Frieder Obbelode , Hermann Vogel , Wilhelm Wolfgang Hoepker , Axel Nierhaus , Stephan Braune , Guido Sauter , Klaus Pueschel , and Stefan Kluge Metrics Cited byAutopsyDeath at Hospital and Medical Liability: Investigation of Medical Interventions with Fatal Outcome by Post-mortem Computed TomographyPostmortem imaging findings and cause of death determination compared with autopsy: a systematic review of diagnostic test accuracy and meta-analysisDifferentiation of hemopericardium due to ruptured myocardial infarction or aortic dissection on unenhanced postmortem computed tomographyResearch in forensic radiology and imaging; Identifying the most important issuesHow does post-mortem imaging compare to autopsy, is this a relevant question?Autopsy: PediatricInvestigation of medical intervention with fatal outcome: the impact of post-mortem CT and CT angiographyWho Will Do My Autopsy?Imaging in forensic radiology: an illustrated guide for postmortem computed tomography technique and protocolsCan cross sectional imaging contribute to the investigation of unexplained child deaths? A literature reviewAutopsyPost-mortem diagnosis: evolving a team approachBildgebung zur Klärung des BehandlungsfehlervorwurfsMessages from the morgue to rheumatology: from Chagas disease to giant cell arteritis 17 January 2012Volume 156, Issue 2 Page: 158-159 Keywords Autopsy Computed axial tomography Diagnostic radiology Forensics Imaging techniques Magnetic resonance imaging Patients Pulmonary embolism Radiologists Systematic reviews ePublished: 17 January 2012 Issue Published: 17 January 2012 Copyright & PermissionsCopyright © 2012 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
No takes yet. Share an insight, caveat, or question.
Burton et al. (2012) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: