The aim of the work was to investigate the nerve grown factor (NGF) level in the blood serum in patients with melancholic depression (MD). The investigated group consists of 23 patients. At admission in the clinic (before any antidepressive treatment) the NGF concentration in patient’s serum was 278.28 ± 43.68 pg/mL that was significantly higher in comparison with controls 239.51 ± 22.15 pg/mL, (p 0.05), respectively. It is supposed, that the increased NGF level in serum of the MD patients can be connected with the impairment of the functioning of the brain-blood barrier and the increase of its permeability for the NGF.
No takes yet. Share an insight, caveat, or question.
Узбеков et al. (2023) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: